Course in Population Pharmacokinetics (Level 1)

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The next session is planned on 3 – 8 March 2014.

For what purpose?

  • To get a sound grounding in population pharmacokinetic concepts, model estimation and evaluation
  • To get strategies for model building

For whom?

  • You want to clearly understand each part of a population pharmacokinetic model?
  • You know that the likelihood/objective function is something very important but you don’t feel very comfortable with it?
  • You want to know everything about the old/new estimation methods (SAEM, FO, FOCE, FOCE-I etc) and what are the pros and cons of each method?
  • You feel lost with all the new model evaluation metrics (EWRES, WRES, NPDE, CWRES, ECWRES etc) and want to learn more on VPCs and other stuff?
  • You want to know more about shrinkage?
  • You feel lost with all the methods for covariate selection (ascending, descending, automatic model building, use of EBEs)?
  • You would like to get some decision rules to guide you during the model building?
  • You have some academic questions you never dared to ask?

Then this course is made for you!

Prerequisite for the course:

  • Basic knowledge and experience in classical pharmacokinetic modeling
  • Basic knowledge in statistics


This course is truly a mix between an academic and professional course. All lectures will be given on a blackboard in an “academic spirit” and hands-on computer exercises will be carried out using the last version of NONMEM and R software.

See the Course Agenda for more details.

On the last day of the course (Saturday morning), you will be free to take an exam and a diploma will be delivered based on the results of this exam. Otherwise, a certificate of attendance will be delivered.

You will be required to bring your own laptop. One month prior to the course, you will receive the instructions to download and install R software on your computer. You will also receive a document with the main commands in R that will be used during the course. NONMEM software (version 7) will be installed on your computer on the first day of the course and will be removed at the end of the course.

Workshop size

The size will be kept small (15 per session) to maximize interaction between participants and tutors.

Registration Procedure

You can register for the next session by completing the form given here. You will then be contacted by Ismeline Mathet. She will give you further instructions for the payment of registration fees and will ask for some personal information in order to deliver the diploma or certificate of attendance. If you do not receive this email, please contact directly Ismeline Mathet.

Registration fees

Registration fees are 3000 € for participants from the Industry and 2250 € for academics and regulatory people. These fees include the course, coffee break and everyday lunch from Monday to Saturday.

Course location

Ecole Nationale Vétérinaire de Toulouse (Vet’ School)
23, chemin des Capelles
31076 Toulouse cedex, France

You will find here some useful information for accomodation and travel.

Feel free to register now